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292 articles · Updated daily
🩺 Doxycycline

Doxycycline in Children Under 8: Why the Tooth-Staining Rule Changed

Older tetracyclines stained children's developing teeth, but doxycycline behaves differently. Here is the evidence that led experts to endorse short courses for tick-borne infections.

pediatricsdental safetyrickettsial disease
✍️ Dr. James Harmon, Research Correspondent · 2026-09-28 Read →
💉 Azithromycin

Azithromycin and QT Prolongation: What the Heart-Risk Evidence Shows

A 2012 Vanderbilt study linked azithromycin to a small rise in cardiovascular death, prompting an FDA warning. Here is what it found, who is at risk, and what later research added.

cardiac safetyqt intervalpharmacovigilance
✍️ Dr. James Harmon, Research Correspondent · 2026-09-28 Read →
⚗️ Mebendazole

Kato-Katz Stool Testing, Worm Egg Counts, and Mebendazole Treatment

The Kato-Katz test counts worm eggs to grade infection as light, moderate or heavy. It often misses light infections, which affects how mebendazole's effectiveness is judged.

diagnosticsparasitologyhelminths
✍️ Dr. James Harmon, Research Correspondent · 2026-09-28 Read →
🌿 Albendazole

Cutaneous Larva Migrans: Diagnosis and Albendazole Treatment

Cutaneous larva migrans is diagnosed by its appearance, not by lab tests, and albendazole treatment length is chosen by response and extent, not a fixed calendar.

diagnosisdosingdermatology
✍️ Dr. James Harmon, Research Correspondent · 2026-09-22 Read →
🧬 Hydroxychloroquine

Hydroxychloroquine and G6PD Deficiency: Understanding the Risk

Hydroxychloroquine, chloroquine, and primaquine all carry warnings for G6PD deficiency, but their actual hemolysis risk differs sharply by chemistry and dose.

G6PD deficiencysafetymechanism
✍️ Dr. James Harmon, Research Correspondent · 2026-09-22 Read →
🌿 Albendazole

Albendazole Monitoring: Liver Enzymes and Blood Counts Explained

Long albendazole courses for hydatid disease and neurocysticercosis are effective but require scheduled liver and blood tests to catch reversible toxicity early.

safety monitoringhepatotoxicitydosing
✍️ Dr. James Harmon, Research Correspondent · 2026-09-22 Read →
⚗️ Mebendazole

Mebendazole: Why One Pill Cures Pinworm But Not Whipworm

Mebendazole's dosing isn't arbitrary — single-dose and three-day regimens exist because pinworm, hookworm and whipworm live differently in the gut.

dosingefficacyhelminths
✍️ Dr. James Harmon, Research Correspondent · 2026-09-22 Read →
🔭 Praziquantel

Praziquantel and Fatty Meals: The Science Behind Dosing Rules

A fatty meal can markedly change how much praziquantel reaches the bloodstream. Here is the pharmacology behind that effect and how dosing guidance accounts for it.

dosingpharmacokineticsfood interaction
✍️ Dr. James Harmon, Research Correspondent · 2026-09-22 Read →
🩺 Doxycycline

Doxycycline for Early Syphilis: What the Evidence Really Shows

For penicillin-allergic patients, doxycycline is a real alternative for early syphilis—but the evidence behind it is thinner than most people realize.

stidosingalternative therapy
✍️ Dr. James Harmon, Research Correspondent · 2026-09-21 Read →